LaGrange lost a heartbreaker to visiting Ave Maria, falling 12-11 in three overtimes. The Panthers (1-5) had rallied from a seven goal halftime deficit to force overtime.
The Gyrenes shut down the Panthers the rest of the half, scoring six unanswered goals to build a 9-2 lead at halftime.
Murphy scored her third goal in a five-minute span to keep the Panthers within striking distance. Trailing 11-6 with 16 minutes left, the Panthers got goals from five different players to force overtime.
The Panthers controlled the ensuing draw control and held the ball for a possible winning shot. Murphy's free position shot in the closing seconds was turned away as the two teams went to overtime.
Ave Maria got the game-winner in the third overtime. Lydia Buckley's fifth goal of the game gave the Gyrenes the 12-11 win.
The Panthers host Greensboro and Ferrum on Saturday and Sunday in USA South games.