The wins upped the Panthers to 16-6 on the season, while the Scotties dropped to 10-12.
The home runs gave Jiles six on the season, which leads the team and the USA South. She drove in four runs to give her a team-leading 22 RBIs.
Wolfe threw a complete game in the first game, limiting the Scotties to the two hits in raising her record to 8-3. She did not walk a batter and struck out five.
Courtney Beshel went 4-for-6 in the two games, that included her first home run of the season. She also had two doubles, scored three runs and had three RBIs.
In the first game, Beshel led off the fourth inning with her home run for 1-0 lead. Jiles' lead off home run started a three-run sixth inning. Beshel drove in the final two runs with a double in the seventh for the 6-0 final margin.
In the second game, Wolfe gave Kara Patterson (3-0) all the runs she would need with a three-run home run in the first inning. It was the fourth home run of the season for Wolfe.
Patterson pitched all five innings, as the game was called on the 8-run mercy rule. She also allowed only two hits, the one run, walked one and struck out three.
Wolfe drove in her fourth run of the game with a single in the second. Jiles' second home run of the night, a three-run shot in the third inning, put the Panthers up 7-0.
The Panthers finished their scoring with five runs in the fourth inning. The only hit of the inning was a bases-loaded triple by Adrienne Little. The Panthers took advantage of three walks and a hit batter in the inning.
The Panthers will play USA South doubleheaders at Averett on Saturday and at Greensboro on Sunday.