The Panthers shot a team score of 294 over the par 72 Benvenue Country Club course. They lead top-seeded Methodist and Christopher Newport by four shots heading into Sunday's final round.
Liang shot a tournament best round of five-under par 67 after a first round 78. He is at 145 for the tournament.
Howard leads Liang by one shot in the individual standings. He shot a two-under par 70 and has an even par total of 144.